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DMSO
Reprinted and edited from 1998 writing of Stephen B. Edelson.
We thank Steven B. Edelson for this concise compilation of DMSO properties.
DMSO -- dimethyl sulfoxide or dimethyl sulfate oxide is
a substance derived in the processing wood pulp. Although it has a number
of healing properties and has been known for a long time it is practically
unknown to allopathic (western) doctors in the United States.
DMSO is not a drug in the usual sense, since a drug treats disease
symptoms. DMSO treats altered cellular function of/or damaged cells. The cells
become healed and restored by changing and
stabilizing their “fluid structure.” (I am neither aware of this
property, nor I am aware of this term. For this very reason I do not
dispute it -- I just do not know -- Dr. Kulisz.) As a result DMSO is very helpful
in illnesses like arthritis and immune
system disease, and they are very helpful in acute inflammatory pain
syndromes.
DMSO tends to build up white blood cells and increase immune production of
MIF (migration inhibitory factors) of macrophages. Thus, the immune system is
made more effective by allowing macrophages to move more quickly. Thus DMSO
modulates lymphocytes, and it therefore reactivates the production of MIF. It
also diminishes allergic
reactions by unfolding the cell membrane and making more cell receptor sites
available to attachment by specific antigens.
The modulating effect of DMSO on lymphocytes also tends to increase the
production of lymphokines (chemical immune cell mediators) such as interferon.
It potentiates cell mediated immunity and can be effective in multiple
sclerosis, systemic lupus,
erythematosus, rheumatoid arthritis, thyroiditis, ulcerative
colitis, cancer, etc.
Therapeutic Properties:
- It blocks pain by interrupting conduction in the small c-fibers, the non-myelinating
nerve fibers.
- It is anti-inflammatory.
- It is anti bacterial, fungal and viral.
- It transports all molecules (drugs, etc.) across cell membranes.
- It reduces the incidence of platelet thrombi (clots in vessels).
- It effects cardiac contractility by inhibiting calcium to reduce the
workload of the heart.
- It is a vasodilator, probably related to histamine release in the cells
and to prostaglandin inhibition.
- It softens collagen.
- It is a scavenger of the hydroxyl free radical.
- It stimulates the immune system.
- It is a potent diuretic.
- It increases interferon formation.
- It stimulates wound healing.
Physico-Chemical Properties:
- It is a simple small molecule with unusual properties.
- An exothermic reaction occurs when DMSO is diluted with water (heat is
generated).
- Hydroxyl radicals (OH), which are free
radicals (oxidants), are ubiquitous and highly injurious to cells—and
thus health. DMSO neutralizes (quenches) these free radicals. (It is a free
radical scavenger.)
- DMSO substitutes for water in the living cell—it can destroy intracellular
free radicals. No other antioxidant can do that.
- DMSO increases the permeability of cell membranes yielding a flushing
effect of toxins from intracellular location to extracellular.
- It is an antidote to allergic
reactions.
- It can penetrate any cell wall; thus it can get where most chemicals
can’t.
- It has a very low index of any toxicity.
- Allergic reactions to DMSO can occur but they are uncommon.
DMSO has a myriad of applications in medicine. Some are so dramatically
effective that the concept of such therapy just boggles the mind!
References:
- Szmant, H. Harry. Physical properties of dimethyl sulfoxide and its
function in biological systems, Biological Actions of Dimethyl
Sulfoxide ed. by Stanley W. Jacob and Robert Herschler. (New York:
New York Academy of Sciences, 1975), pp. 20-23.
- Barfeld, H., and T. Atoynatan. N-acetylcysteine inactivates migration
inhibitory factor and delayed hypersensitivity reactions. Nature new
Bio., 231:157-159, 1971.
- Barfeld, H., and T. Atoynatan, Cytophilic nature of migration inhibitory
factor associated with delayed hypersensitivity, Proc. Soc. Exp. Biol.
Med., 139:497-501, 1969.
- Tschope, M., cited in Raettig, H. “The potential of DMSO in experimental
immunology,” Dimethylsulfoxyl, Internationales Symposium in
Wien. G. Laudahn and K. Getrich, eds.; 54. Saladruck, Berlin, Germany, 1966.
- Engel, M.F. Ann. N.Y. Acad. Sci., 141:638, 1967.
Reprinted and edited from 1998 writing
of Stephen B. Edelson. We thank Steven B. Edelson for this concise compilation
of DMSO properties.
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